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2018 Glenn Foundation for Medical Research Breakthroughs in Gerontology (BIG) Grants

Grants to USA Assistant Professors and Professors
for Research Projects Related to the Aging Process

Agency Type:

Foundation / Corporation

Funding Source:

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Glenn Foundation for Medical Research and American Federation for Aging Research (AFAR)

Deadline Date:



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Large grants to USA full-time faculty members at the rank of Assistant Professor or higher for research projects related to aging. This initiative provides timely support for a small number of research projects that are relatively high risk, but which offer significant promise of yielding transforming discoveries in the fundamental biology of aging.

Projects which build on early discoveries that show translational potential for clinically-relevant strategies, treatments, and therapeutics, addressing human aging and health span are also considered.

Projects that focus on specific diseases or on assessment of health care strategies will receive lower priority, unless the research plan makes clear and direct connections to fundamental issues in the biology of aging and/or on the translational aspects of basic discovery to human aging and health-span.

Two three-year awards will be made in 2018, at the level of $300,000 total ($100,000 per year), of which a maximum of 8% may be used for indirect expenses or institutional overhead. The amount and the duration of the award may be modified if during the review process or at the funding stage it is evident that such modifications would better serve the objectives of the program.

Applications are reviewed based on the following criteria:

- Qualifications and research record of the applicant
- Quality, creativity, promise,
and feasibility of the proposed research that will lead to improved understanding of basic aging processes and/or translational potential and relevance to human aging and health span.
- Excellence of the research environment

GrantWatch ID#:

GrantWatch ID#: 165362

Number of Grants:


Estimated Size of Grant:

Grants totaling $300,000 ($100,000 per year for three years) will be awarded, of which a maximum of 8% may be used for indirect expenses or institutional overhead.

Term of Contract:

Three-year awards will be made in 2018. The award start date is July 1, 2018.

Additional Eligibility Criteria:

To be eligible, applicants must at the time they submit their proposal be full-time faculty members at the rank of Assistant Professor or higher. To be competitive at the Assistant Professor level, a candidate would be expected to have established R01 or equivalent funding. The BIG award is not intended to substitute for the R01 funding mechanism, but rather to provide support for novel “breakthrough” research projects in established laboratories. A strong record of independent publication beyond the postdoctoral level is a requirement. Individuals who are employees in the NIH Intramural program are not eligible.

The proposed research must be conducted at qualified nonprofit setting in the United States.

Former AFAR Research Grant awardees may apply. If you are applying for a 2018 AFAR Research Grant, you may not also apply for the 2018 Glenn Foundation for Medical Research BIG Award. Principal Investigators of the Paul F. Glenn Centers for Biology of Aging Research are not eligible to apply.

Pre-Application Information:

Application Procedures:

- The deadline of receipt of the Letters of Intent (LOI) is January 22, 2018 at 5:00 p.m. EST.
- Click on the link in the Supporting Documents section below to download the instructions for the Glenn/AFAR BIG LOI.
- Incomplete or improperly completed LOIs cannot be considered.
- The Letters of Intent will be reviewed by a committee. Applicants will be notified by March, and a subset of applicants will be invited to submit a full application. The deadline for receipt of full applications will be in April 2018.
- All LOI candidates who are invited to submit applications must have it endorsed by their institution. Final awards are announced by early June. AFAR will not provide reviewer critiques to any applicants at any review level.
- Recipients of this award are expected to attend the AFAR Grantee Conference. The purpose of the meeting is to promote scientific and personal exchanges among recent AFAR grantees and experts in aging research.

Additional Notes:

If you are using animals in your research, please review Principles of Animal Use for Gerontological Research:


Contact Information:

Before starting your grant application, please review the funding source's website listed below for updates/changes/addendums/conferences/LOIs.

Questions about eligibility and suitability of research project can be addressed to

All LOIs should be submitted as PDFs to the email

URL for Full Text (RFP):

Geographic Focus:

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